Composition comprising a mixture of clopidogrel and droloxifene

摘要

Composition comprising a mixture of clopidogrel and droloxifeneA composition comprising a mixture of droloifene, preferably droloxifene citrate, and clopidogrel, preferably clopidogrel bisulphate, for use in the treatment or prevention of a disorder associated with the loss of normal adult tissue architecture including autoimmune diseases, vascular disorders, asthma, allergic rhinitis or chronic obstructive pulmonary disease (COPD), osteoporosis, tumour growth, organ transplant rejection, psoriasis, allergies, Alzheimer's disease Parkinson's disease, Huntington's disease and traumatic brain injury. Preferably the molar ratio of the two components within the composition is between 10:1 and 1:10. A composition comprising a compound formed by chemically linking droloifene and clopidogrel, in particular a compound of formula (I), for use in treating an inflammatory disorder is also provided.