Quencher added dendrimer dyes for detection of Ming

摘要

The present invention presents may be activated by converting it to a fluorescent state acceptor / quencher of single molecular assembly during the design quencher addition of high absorbance for "Daidoron". Quencher, are activated by non-covalently bound to the (FAP) fluorophore activating peptide expressible complementary unique. In this method, the quencher acts as a uniform switch, receives the energy efficiently from the donor molecule antenna dendron, and emitted as fluorescence it only when it is activated by the binding. The total absorbance of multiple dyes on the antenna, a dramatic enhancement in luminance efficiency of the probe in the imaging system standard. One probe set having to specifically target the expression tag to activate the fluorescence of Daidoron by this approach, the brightness exceptional is provided.