Being production manner of the antibody which immunity uniquely is joined the physiological active intact parathyroid hormone (PTH) the parathyroid hormone which has the peptide antigen null physiological

摘要

The parathyroid hormone (PTH) the amino acid residue 2 12, the method of producing the antibody, and that kind of antibody which possess the affinity for the peptide antigen and that kind of peptide antigen which correspond to the 1 12, the 2 15 and the 1 15. Production method of the antigen, the antibody and the antibody due to this invention, the serum, the blood plasma, and/or is useful in decision of the level of physiological active intact PTH in the cell nutrient medium. That kind of antibody furthermore is kind intersection reactivity high-level, but vis-a-vis the PTH peptide fragment which is not the whole it possesses the intersection reactivity which is decreased substantially, the possession it does not do most reactivities vis-a-vis the recognition region of the first amino acid residue of PTH.