首页> 外国专利> Photosensitizer, protein cleaving agent, protein cleaving method, sugar molecule cleaving agent, sugar molecule cleaving method, and photodynamic therapeutic agent

Photosensitizer, protein cleaving agent, protein cleaving method, sugar molecule cleaving agent, sugar molecule cleaving method, and photodynamic therapeutic agent

机译:光敏剂,蛋白质裂解剂,蛋白质裂解方法,糖分子裂解剂,糖分子裂解方法和光动力治疗剂

摘要

[PROBLEMS] To provide a novel photosensitizer, methods of cleaving a protein and cleaving a sugar molecule with light irradiation, and a protein-cleaving agent and sugar molecule-cleaving agent for use in these methods. [MEANS FOR SOLVING PROBLEMS] A compound represented by the following general formula (I) or a salt thereof generates active oxygen upon light irradiation and functions to cleave a protein and sugar molecules. The compound or salt is hence useful in applications such as a photosensitizer, protein-cleaving agent, sugar molecule-cleaving agent, and photodynamic therapeutic agent. [Chemical formula 1] (I) (In the formula, RSUB1/SUB to RSUB8/SUB each is hydrogen or a hydroxylated substituent, provided that at least one of RSUB1/SUB to RSUB8/SUB is a hydroxylated substituent.)
机译:[问题]为了提供新型的光敏剂,利用光照射来切割蛋白质并切割糖分子的方法,以及用于这些方法中的蛋白质切割剂和糖分子切割剂。 [解决问题的手段]由以下通式(I)表示的化合物或其盐在光照射时产生活性氧,并具有裂解蛋白质和糖分子的功能。因此,该化合物或盐可用于诸如光敏剂,蛋白质裂解剂,糖分子裂解剂和光动力治疗剂的应用中。 [化学式1](I)(式中,R 1 至R 8 分别为氢或羟基取代基,条件是R 中的至少一个1 至R 8 是羟基取代基。)

著录项

  • 公开/公告号JP5046029B2

    专利类型

  • 公开/公告日2012-10-10

    原文格式PDF

  • 申请/专利权人 学校法人慶應義塾;

    申请/专利号JP20070507210

  • 发明设计人 戸嶋 一敦;

    申请日2006-03-10

  • 分类号C09K3;C07C50/34;C09B1;C07H15/18;A61K31/122;A61K31/704;A61P43;C07C46;C07K1/12;A61P35;A61P31/04;A61P31/12;A61P3/04;A61P3/10;

  • 国家 JP

  • 入库时间 2022-08-21 17:37:27

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