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METHOD FOR THE QUANTITATIVE AND QUALITATIVE CHARACTERIZATION OF ANTIGEN-SPECIFIC T CELLS RECOGNIZING A SPECIFIC ANTIGEN

机译:识别特定抗原的抗原特异性T细胞的定性和定性方法

摘要

The invention relates to a method for sensitive quantitative and/or qualitative analysis of target T cells comprising the steps a) enrichment of said cells from a mixture of said cells and other cells in a sample by the use of one or more activation markers expressed on antigen-activated T cells in a parallel cell sorting process and b) analysis of the cells of step a).;The invention relates also to a method of diagnosing diseases based on the analysis of the target T cells.
机译:本发明涉及用于靶T细胞的灵敏定量和/或定性分析的方法,其包括以下步骤:a)通过使用在细胞上表达的一种或多种活化标记,从样品中的所述细胞和其他细胞的混合物富集所述细胞。平行细胞分选过程中的抗原激活的T细胞和b)步骤a)中的细胞分析。;本发明还涉及基于靶T细胞分析的疾病诊断方法。

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