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Method for using DNA repair capacity as a biomarker of breast cancer risk in women
Method for using DNA repair capacity as a biomarker of breast cancer risk in women
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机译:使用DNA修复能力作为女性乳腺癌风险生物标志物的方法
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摘要
The present invention presents a method for using DNA repair capacity (DRC) as a blood biomarker to calculate the risk of a female subject developing breast cancer obtained from a blood sample by using a luciferase reporter gene method that permits calculating a percent DRC for the subject. A subject with a percent DRC below 3.1% is considered as being at risk for breast cancer and a subject with a percent DRC above 3.1% as being at low risk for breast cancer. This method comprises a further estimation of an adjusted risk of the subject to develop breast cancer using a logistic regression equation in which the DRC value is included as one of the variables.
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