Methods and compositions for Intrathecal Administration of iduronate-2-sulfatase, container for Intrathecal Administration, System

摘要

1. Claim 1: provide a stable formula for library management, which contains an iduronat-2-sulfatasa (I2S) protein;Sal and a surface of polysolbato.requirements 13:, The formula also includes a ph.requirement 23 regulator: a stable internal management formula containing ldurnato-2-sulvatasa (I2S) protein in a concentration range of about 1-300 mg / M; a nati in a concentration range of about 154 mm; a polyurethane 20, a. The concentration is about 0.005%;And the pH value is about 6.0.