use of compounds in the preparation of medicaments for the prevention or treatment of diabetic nephropathy, complication of renal disorder and dyslipidemia, reduced serum lipid and uric acid levels, and increased creatinine clearance and renal function

摘要

USE OF COMPOUNDS IN THE PREPARATION OF MEDICINES FOR THE PREVENTION OR TREATMENT OF DIABETIC NEPHROPATHY, COMPLICATION OF KIDNEY DISORDER AND DYSLIPIDEMIA, REDUCING THE LEVELS OF LIPIDS AND URICIC ACID IN THE SERUM, AND INCREASING THE CREATINE'S CEREALARANCE methods, compounds and compositions for the prevention or treatment of kidney disorders or chronic kidney diseases, including kidney diseases, such as diabetic kidney diseases. The invention generally includes administration to individuals of 1,3-propanedisulfonic acid or a pharmaceutically acceptable salt thereof, e.g., 1,3-propanedisulfonic acid sodium salt. The present invention also relates to methods, compounds and compositions for the prevention and / or treatment of complications of kidney disorders. The invention also relates to methods, compounds and compositions for the prevention and / or treatment of dyslipidemia and, more particularly, for the reduction of harmful levels of serum lipids, especially cholesterol and triglycerides in diabetic patients.