首页> 外国专利> Pharmaceutical Combination comprising an Antibody that specifically recognizes to CD38, and Cyclophosphamide, where the Antibody is capable of eliminating a CD38 + cells by apoptosis, Antibody dependent cell-mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC).

Pharmaceutical Combination comprising an Antibody that specifically recognizes to CD38, and Cyclophosphamide, where the Antibody is capable of eliminating a CD38 + cells by apoptosis, Antibody dependent cell-mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC).

机译:药物组合,其包含特异性识别CD38的抗体和环磷酰胺,其中该抗体能够通过凋亡,抗体依赖性细胞介导的细胞毒性(ADCC)和补体依赖性细胞毒性(CDC)消除CD38 +细胞。

摘要

Pharmaceutical combinations comprising an Antibody that specifically recognizes at least CD38 and Cyclophosphamide; and use of CD38 Antibody that recognizes specifically for the treatment of squamoR.
机译:药物组合,其包含至少能特异性识别CD38和环磷酰胺的抗体;和CD38抗体的用途,该抗体专门用于治疗squamoR。

著录项

  • 公开/公告号CL2011001256A1

    专利类型

  • 公开/公告日2012-01-27

    原文格式PDF

  • 申请/专利权人 SANOFI;

    申请/专利号CL20110001256

  • 发明设计人 LEJEUNE PASCALE;VRIGNAUD PATRICIA;

    申请日2011-05-27

  • 分类号A61K31/675;A61K39/395;A61P35/00+;

  • 国家 CL

  • 入库时间 2022-08-21 17:25:21

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