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INJECTION MEDICATION FORM FOR THE TREATMENT OF ACUTE ISCHEMIC STROKE AND CRANIAL INJURY, METHOD OF ITS MANUFACTURE AND USE
INJECTION MEDICATION FORM FOR THE TREATMENT OF ACUTE ISCHEMIC STROKE AND CRANIAL INJURY, METHOD OF ITS MANUFACTURE AND USE
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机译:治疗急性缺血性脑卒中和颅脑损伤的注射药形式,制造方法和使用
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摘要
Injectable dosage form for the treatment of acute stroke and traumatic brain injury includes, as an active ingredient, a therapeutically effective amount of the heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro and at least one substance selected from the group of antioxidants including β-carotene , retinol acetate, α-tocopherol acetate, ascorbic acid, lutein, quercetin, rutin (vitamin P), dihydroquercetin, butylhydroxytoluene, α-lipoic acid, L-carnitine, succinic acid, and optionally at least one auxiliary a member selected from the group consisting of stabilizers, prolongatory, buffering agents, emulsifying agents, solubilizing agents, solvents, fillers, preservatives, and other auxiliary substances permitted for medical application. The drug provides a high neuroprotective effect in acute severe damage to the central nervous system on different models of stroke and traumatic brain injury, and also has high stability and a long period of use of at least 3 years.
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