A process of fermentation, purification and production of recombinant soluble Tumour Necrosis Factor alfa Receptor (TNFR) - human IgG Fc fusion protein

摘要

The present invention relates to the use of novel fermentation and chromatographic procedures separately and jointly for the production of recombinant soluble Tumour Necrosis Factor Alfa receptor (TNFR) - Human IgG Fc fusion protein, in biologically active form from fluids, especially mammalian host cell culture supernatants.