首页> 外国专利> USE OF AMINO ACID SEQUENCES FROM MYCOBACTERIUM TUBERCULOSIS OR CORRESPONDING NUCLEIC ACIDS FOR DIAGNOSIS AND PREVENTION OF TUBERCULAR INFECTION, DIAGNOSTIC KIT AND VACCINE THEREFROM.

USE OF AMINO ACID SEQUENCES FROM MYCOBACTERIUM TUBERCULOSIS OR CORRESPONDING NUCLEIC ACIDS FOR DIAGNOSIS AND PREVENTION OF TUBERCULAR INFECTION, DIAGNOSTIC KIT AND VACCINE THEREFROM.

机译：利用结核分枝杆菌的氨基酸序列或相应的核酸诊断和预防肺结核感染，诊断试剂盒和疫苗。

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摘要

The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease. 展开▼

机译：本发明涉及基因序列或其部分的用途，其特征在于它们属于当前感染人巨噬细胞的结核分枝杆菌中体外和离体诱导，抑制或保守的基因类别，以及相应的肽或共有肽或蛋白质。用于制备用于诊断和预防活动性或潜伏性疾病的特定生物标记。展开▼

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公开/公告号WO2012011144A2

专利类型

公开/公告日2012-01-26

原文格式PDF

申请/专利权人 AMICOSANTE MASSIMO;MARIANI FRANCESCA;COLIZZI VITTORIO;SALTINI CESARE;4ROMAPEPTIDI S.R.L.;
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申请/专利号WO2011IT00266

发明设计人 AMICOSANTE MASSIMO;MARIANI FRANCESCA;COLIZZI VITTORIO;SALTINI CESARE;
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申请日2011-07-25

分类号A61K38/16;C07K14/35;C07K16/12;C12N5;C12Q1/68;G01N33/569;

国家 WO

入库时间 2022-08-21 17:18:07

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1. Evaluation of anti-tubercular activity of linolenic acid and conjugated-rlinoleic acid as effective inhibitors against Mycobacterium tuberculosis [J] . Won Hyung Choi 亚太热带医药杂志（英文版） . 2016,第002期

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12. Human retroviruses and AIDS 1996. A compilation and analysis of nucleic acid and amino acid sequences [R] . Myers, G. , Foley, B. , Korber, B. , 1997

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