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COMPONENT PROTEIN PA1698 FOR TYPE-III SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA

机译:铜绿假单胞菌Ⅲ型分泌系统的组分蛋白PA1698

摘要

An object is to provide an antibody and a vaccine composition which have an ability to practically prevent or treat a Pseudomonas aeruginosa infection, and which can cope with the diversity of clinical isolates derived from patients infected with Pseudomonas aeruginosa. According to the present invention, an antibody against a PA1698 protein that is a type III secretion system component protein of Pseudomonas aeruginosa or against a peptide of the protein, and a vaccine composition comprising the protein or the peptide are provided.
机译:一个目的是提供一种抗体和疫苗组合物,该抗体和疫苗组合物具有实际上预防或治疗铜绿假单胞菌感染的能力,并且可以应对源自被铜绿假单胞菌感染的患者的临床分离株的多样性。根据本发明,提供了针对作为铜绿假单胞菌的III型分泌系统成分蛋白质的PA1698蛋白质或该蛋白质的肽的抗体,以及包含该蛋白质或该肽的疫苗组合物。

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