PROBE FOR DETECTING POLYMORPHISM IN CYP3A GENE, METHOD OF DETECTING OF POLYMORPHISM, METHOD OF EVALUATING DRUG EFFICACY, AND REAGENT KIT FOR DETECTING POLYMORPHISM

摘要

PURPOSE: A probe for detecting CYP3A gene polymorphism is provided to simply and sensitively detecting the polymorphism. CONSTITUTION: A probe for detecting CYP3A gene polymorphism is P1, P1', P2, P2', P3, P3', P4, P4', P5 or P5' fluorescence-labeled oligonucleotide. The fluorescence-labeled oligonucleotide recognizes 401th base polymorphism of sequence number 1. The fluorescence-labeled oligonucleotide has a fluorescence-labeled base at 3' terminal. The probe has a base of sequence number 37, 38, 39, 41, 43, or 45.