Method of preparing chiral ß-sustituted ?-lactol, ?-lactone and chiral ß-sustituted ?-lactol, ?-lactone prepared by thereof

摘要

The present invention is beta position is substituted chiral gamma- raktol and chiral gamma- lactone and its manufacturing method prepared by chiral gamma - raktol and chiral gamma - lactone relates to the method and easy to be used in many beta position intermediate in the synthesis of a chiral substance has been substituted by a simple process than the conventional gamma - raktol and chiral gamma- lactone can be obtained. Also , without the use of heavy metal catalysts are high enantiomeric selectivity beta position is substituted chiral gamma - raktol and chiral gamma - lactone can be obtained in high yield