FIELD: medicine.;SUBSTANCE: there are presented method for detecting a renal disease accompanied by high renal excretion of megaline involving the quantitative measurement of human megaline in a sample by immune-enzyme assay or agglutination method. There are also presented: megaline as a new marker for detecting the renal disease, the use of megaline as such marker, as well as a kit used for diagnosing consisting of a ligand able to bind with human megaline.;EFFECT: use of the invention enables early diagnosing of renal tubule insufficiency by simple and fast, but along with this specific manner.;21 cl, 4 dwg, 2 tbl, 5 ex
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机译：领域：药物：本发明提供了一种检测肾脏疾病并伴有巨环肾高排泄的方法，该方法涉及通过免疫酶法或凝集法定量测定样品中人类巨环的含量。还提出了：megaline作为检测肾脏疾病的新标志物，megaline作为此类标志物的用途，以及用于诊断由能够与人megaline结合的配体组成的试剂盒。效果：本发明的用途通过这种简单方式可以快速，简便地及早诊断肾小管功能不全。; 21 cl，4 dwg，2 tbl，5 ex
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