Diagnosing diseases of central nervous system e.g. primary lymphoma, comprises determining content of microRNA highly diagnostic for presence or absence of disease in a sample of cerebrospinal fluid, and comparing with a reference value

摘要

Diagnosing diseases of central nervous system, preferably primary lymphoma, inflammatory changes, neuroepithelial and meningeal tumors, comprises determining the content of at least one microRNA highly diagnostic for the presence or the absence of disease in a sample of cerebrospinal fluid, and comparing with a reference value. An independent claim is also included for the use of one microRNA, in particular miR-21, miR-19b and miR-92a or its antisense oligonucleotide or a target of these microRNAs for the treatment of CNS illnesses. ACTIVITY : CNS-Gen.; Cytostatic; Antiinflammatory. MECHANISM OF ACTION : None given.