首页> 外国专利> Bypassing end replication defect comprises replacing RNA primers by RNAse H from DNA strand during cell division, which activates new DNA strand e.g. by neurotransmitters, hence new cell division arises and chromosomes do not become shorter

Bypassing end replication defect comprises replacing RNA primers by RNAse H from DNA strand during cell division, which activates new DNA strand e.g. by neurotransmitters, hence new cell division arises and chromosomes do not become shorter

机译:绕过末端复制缺陷包括在细胞分裂过程中用DNA链中的RNA酶H代替RNA引物,从而激活新的DNA链,例如:通过神经递质,因此会出现新的细胞分裂,染色体不会变短

摘要

Bypassing end replication defects comprises: replacing RNA primers by an RNAse H from a DNA strand during cell division, which activates the new DNA strand by electrical impulses and neurotransmitters from the growth hormones and hence a new cell division arises and the chromosomes do not become shorter with each cell division, in comparison with the conventional division, where a piece (approximately 100 nucleotides) of the telomeres get lost by shortening of the DNA strand, due to the replication of DNA from the 5' to 3' after binding of primers in the presence of DNA-polymerase.
机译:绕过末端复制缺陷包括:在细胞分裂过程中,用DNA链中的RNAse H代替RNA引物,这通过生长激素的电脉冲和神经递质激活新的DNA链,因此发生新的细胞分裂,染色体不会变短与常规细胞分裂相比,在每个细胞分裂中,由于引物结合后DNA从5'到3'的复制,端粒的一部分因DNA链的缩短而丢失(约100个核苷酸)。 DNA聚合酶的存在。

著录项

  • 公开/公告号DE102010056626A1

    专利类型

  • 公开/公告日2011-12-15

    原文格式PDF

  • 申请/专利权人 JERSCH DIETRICH ROLAND;

    申请/专利号DE20101056626

  • 发明设计人 JERSCH DIETRICH ROLAND;

    申请日2010-04-20

  • 分类号C12N15/00;A61M1/34;C12N5/078;

  • 国家 DE

  • 入库时间 2022-08-21 17:05:14

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