APOPTOSIS INHIBITORY PROTEIN LIGAND-ESTROGEN RECEPTOR LIGAND HYBRID COMPOUND, ESTROGEN RECEPTOR DECOMPOSITION INDUCING AGENT UTILIZING THE SAME, AND PROPHYLACTIC AND THERAPEUTIC AGENT FOR BREAST CANCER, CERVICAL CANCER OR OVARIAN CANCER

摘要

PROBLEM TO BE SOLVED: To provide an apoptosis inhibitory protein ligand-estrogen receptor ligand hybrid compound, which specifically decomposes an estrogen receptor expressing in the cancer cells of a breast cancer or the like to induce a cell death by a new mechanism of action.SOLUTION: The apoptosis inhibitory protein ligand-estrogen receptor ligand hybrid compound is represented by general formula (I) (wherein, X represents an apoptosis inhibitory protein ligand specifically bonded to an apoptosis inhibitory protein; Y represents an estrogen receptor ligand specifically bonded to an estrogen receptor; and Z represents a low molecular chain linker bonding both the apoptosis inhibitory protein ligand and estrogen receptor ligand without inhibiting the specific bondability of the apoptosis inhibitory protein ligand and estrogen receptor ligand).