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Screening method of the new medicine candidacy substance which obstructs the target protein - protein interaction for epoch-making new medicine development
Screening method of the new medicine candidacy substance which obstructs the target protein - protein interaction for epoch-making new medicine development
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机译:阻碍靶蛋白-蛋白相互作用的新药候选物质的筛选方法,为划时代的新药开发
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摘要
The present invention relates to a method for screening a substance inhibiting protein-protein interactions, and more particularly to a method for screening a substance inhibiting protein-protein interactions, the method comprising using a protein chip having immobilized thereon spots comprising a mixture of a sol-gel material and a protein. According to the invention, a protein chip can be easily manufactured in a 96-well plate using a sol-gel material, whereby an inhibitor that inhibits protein-protein interactions can be easily screened from a library of natural substances.
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