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Fluorine-containing pyrazole carbonitrile derivative and method for producing the same, and fluorine-containing pyrazole carboxylic acid derivative obtained using the fluorine-containing pyrazole carbonitrile derivative and a method for producing the same.
Fluorine-containing pyrazole carbonitrile derivative and method for producing the same, and fluorine-containing pyrazole carboxylic acid derivative obtained using the fluorine-containing pyrazole carbonitrile derivative and a method for producing the same.
The present invention provides a fluorine-containing pyrazolecarbonitrile derivative and a method for producing the same, and a fluorine-containing pyrazolecarboxylic acid derivative obtained by using the fluorine-containing pyrazolecarbonitrile derivative and a method for producing the same. A fluorine-containing acyacrylonitrile derivative prepared from a fluoroacyl derivative and an aminoacrylonitrile derivative, is reacted with a hydrazine derivative to produce a fluorine-containing pyrazolecarbonitrile derivative represented by Formula (1). In Formula (1), Rf represents an alkyl group having 1 to 6 carbon atoms and substituted with at least one fluorine atom; R1 represents an alkyl group having 1 to 6 carbon atoms and R2 represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or the like. The fluorine-containing pyrazolecarbonitrile derivative represented by Formula (1) is reacted with water to produce a fluorine-containing pyrazolecarboxylic acid derivative.
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机译:本发明提供了一种含氟的吡唑腈衍生物及其制备方法,以及通过使用该含氟的吡唑腈衍生物而获得的含氟吡唑羧酸衍生物及其制备方法。由氟代酰基衍生物和氨基丙烯腈衍生物制得的含氟酰基丙烯腈衍生物与肼衍生物反应,生成式(1)所示的含氟吡唑腈衍生物。式(1)中,Rf表示碳数1〜6且被至少1个氟原子取代的烷基。 R 1表示具有1-6个碳原子的烷基,R 2表示氢原子,具有1-6个碳原子的烷基等。使式(1)表示的含氟吡唑甲腈衍生物与水反应,生成含氟吡唑羧酸衍生物。
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