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DEVICE AND METHOD FOR DETERMINING A BIOLOGICAL, CHEMICAL AND/OR PHYSICAL PARAMETER IN A LIVING BIOLOGICAL TISSUE

机译:确定活体生物组织中生物,化学和/或物理参数的装置和方法

摘要

The invention relates to a device for determining biological, chemical and/or physical parameters in living biological tissue, comprising an energy supply unit, a laser operating unit with at least one laser source directed at the biological tissue, at least one sensor unit for detecting the light scattered back and/or absorbed by the biological tissue, a control unit, a storing and processing unit and an interface for an external data processing unit. The method according to the invention includes execution of a calibrating phase for ascertaining a reference set (R) of reference vectors (Ri), in each case involving independently ascertaining a parameter (BZi), radiating unpolarized laser light onto the biological tissue and registering a measured value vector (Mi) from a series of optical measured variables and executing an interpolation phase for ascertaining an interpolation set (I) of interpolation vectors (Ik), in each case involving radiating unpolarized laser light onto the biological tissue and registering a measured value vector (Mk) from a back-scattered light intensity with a subsequent determination of an interpolated parameter (BKk) from the reference set (R).
机译:本发明涉及一种用于确定活的生物组织中的生物学,化学和/或物理参数的装置,该装置包括能量供应单元,具有至少一个指向生物组织的激光源的激光操作单元,至少一个用于检测的传感器单元。由生物组织散射回和/或吸收的光,控制单元,存储和处理单元以及用于外部数据处理单元的接口。根据本发明的方法包括执行用于确定参考向量(Ri)的参考集合(R)的校准阶段,在每种情况下,都涉及独立地确定参数(BZi),将非偏振激光辐射到生物组织上并进行配准。一系列光学测量变量的测量值向量(Mi)并执行一个插值阶段,以确定插值向量(Ik)的插值集(I),每种情况都涉及向生物组织辐射非偏振激光并记录测量值反向散射光强度的矢量(Mk),然后根据参考集(R)确定内插参数(BKk)。

著录项

  • 公开/公告号US2013237797A1

    专利类型

  • 公开/公告日2013-09-12

    原文格式PDF

  • 申请/专利权人 ARNO MÜLLER;HEINZ-PETER UTZ;

    申请/专利号US201113639574

  • 发明设计人 ARNO MÜLLER;HEINZ-PETER UTZ;

    申请日2011-03-31

  • 分类号A61B5/00;A61B5/145;

  • 国家 US

  • 入库时间 2022-08-21 16:52:56

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