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COMPOUNDS AND METHODS OF MODULATING MITOCHONDRIAL BIOENERGETIC EFFICIENCY THROUGH AN INTERACTION WITH ATP SYNTHASE (COMPLEX V) AND ITS SUBUNITS
COMPOUNDS AND METHODS OF MODULATING MITOCHONDRIAL BIOENERGETIC EFFICIENCY THROUGH AN INTERACTION WITH ATP SYNTHASE (COMPLEX V) AND ITS SUBUNITS
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机译:通过与ATP合酶(复合物V)及其亚基相互作用来调节线粒体生物能效率的化合物和方法
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摘要
The present invention provides, in part, methods of identifying compounds that can bind to an ATP synthase complex, increase bioenergetic efficiency, decrease oxygen consumption or the rate thereof, increase oxygen utilization efficiency, increase cell survival or any combination thereof, and methods of using compounds and/or identified compounds to increase bioenergetic efficiency, increase oxygen utilization efficiency, decrease oxygen consumption, increase cell survival, or any combination thereof.
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