首页> 外国专利> Nucleic acid aptamer capable of binding specifically to pancreatic cancer cells or tissues and use thereof

Nucleic acid aptamer capable of binding specifically to pancreatic cancer cells or tissues and use thereof

机译:能够与胰腺癌细胞或组织特异性结合的核酸适体及其用途

摘要

The present invention relates to a nucleic acid aptamer which can specifically recognize and bind to pancreatic cancer cells or tissues. The nucleic acid aptamer can bind specifically only to pancreatic cancer cells or tissues without binding to normal pancreatic cancer tissue, and thus can be effectively used as a composition for diagnosing and treating pancreatic cancer. In addition, the nucleic acid aptamer can detect not only the terminal pancreatic cancer cell line Capan-1, but also the early pancreatic cancer cell line Panc-1, and thus can be used for early diagnosis of pancreatic cancer, thereby contributing to increasing the survival rate of pancreatic cancer patients.
机译:核酸适体技术领域本发明涉及可以特异性识别并结合胰腺癌细胞或组织的核酸适体。核酸适体可以仅与胰腺癌细胞或组织特异性结合而不与正常胰腺癌组织结合,因此可以有效地用作诊断和治疗胰腺癌的组合物。另外,核酸适体不仅可以检测末端胰腺癌细胞系Capan-1,而且可以检测早期胰腺癌细胞系Panc-1,因此可以用于胰腺癌的早期诊断,从而有助于增加胰腺癌的发生率。胰腺癌患者的生存率。

著录项

  • 公开/公告号US8563711B2

    专利类型

  • 公开/公告日2013-10-22

    原文格式PDF

  • 申请/专利权人 DONG KI LEE;DUA POOJA;

    申请/专利号US201013375347

  • 发明设计人 DONG KI LEE;DUA POOJA;

    申请日2010-06-01

  • 分类号C07H21/04;C12Q1/68;

  • 国家 US

  • 入库时间 2022-08-21 16:46:26

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