Trivariables binding proteins with domains and their uses

摘要

Multivalent binding proteins and multi species, and methods to produce them. Also provided are methods for using and Multispecies multivalent binding proteins present in the Prevention, diagnosis and / or treatment of diseases. Conjugates, Pharmaceutical composition, host Cell Nucleic Acid Molecule, vector. Method for producing Protein.Claim 1: a Binding Protein which comprises a polypeptide Chain.Where the polypeptide Chain comprising VD1 (x1) - N - (x2) - VD2 vd3 - C - N - (x3) n where: VD1 is a First variable domain of the heavy chain; VD2 is a Second variable domain of the heavy chain; vd3 is a Third variable domain of heavy chain; c is a Constant domain of the PES Chain Ada; x1 is a First Connector, a Second Connector x2, X3 is an FC region; and N is 0 OR 1; whereThe Binding Protein have the ability to bind to between one and three target antigens.