Nitrile-containing amide of substituted n-amino acid as a cathepsin cysteine protease inhibitor and pharmaceutical composition comprising the same

摘要

This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.