Combination of carboestirilo and Derivatives of serotonin reuptake inhibitors for the treatment of mood disorders

摘要

Pharmaceutical composition comprising (1) a Derivative of carboestirilo (2) and a serotonin reuptake inhibitor in a pharmaceutically acceptable Carrier. The derivative can be carboestirilo Aripiprazole or a metabolite thereof, which is a dopamine serotonin System Stabilizer.The serotonin reuptake inhibitor can be Venlafaxine, fluoxetine, duloxetine, milnacipran, citalopram, fluvoxamine, paroxetine or sertraline. The pharmaceutical Composition of the present Invention is used for the treatment of patients with mood disorders, particularly Depression or major depressive disorder.