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METHOD FOR PROVIDING INFORMATION FOR THE HISTOLOGICAL CLASSIFICATION OF NON-SMALL-CELL LUNG CARCINOMA USING LIPID PROFILES

机译:利用脂质谱提供非小细胞肺癌组织学分类信息的方法

摘要

The objective of the present invention is to classify the histological type of non-small-cell lung carcinoma in a more accurate, inexpensive, and easy manner using only a small amount of tissue sample. To accomplish the objective of the present invention, a method for providing information for the histological classification of non-small-cell lung carcinoma using lipid profiles comprises the steps of: (a) mixing a matrix and a human tissue to prepare a sample; (b) performing mass spectrometry on the prepared sample; (c) selecting first lipid profile data, which is information on a lipid profile, from the data obtained from the mass spectrometry; and (d) comparing second lipid profile data, which is information on the lipid profile of adenocarcinoma tissue or squamous-cell carcinoma tissue, with the first lipid profile data, in order to provide information for indicating whether the sample is relevant to either adenocarcinoma or squamous-cell carcinoma.
机译:本发明的目的是仅使用少量组织样品以更准确,便宜和容易的方式对非小细胞肺癌的组织学类型进行分类。为了实现本发明的目的,提供一种使用脂质谱为非小细胞肺癌的组织学分类提供信息的方法,包括以下步骤:(a)混合基质和人体组织以制备样品; (b)对所制备的样品进行质谱分析; (c)从质谱法获得的数据中选择第一脂质谱数据,其是关于脂质谱的信息; (d)将第二种脂质谱数据与第一种脂质谱数据进行比较,所述第二种脂质谱数据是关于腺癌组织或鳞状细胞癌组织的脂质谱的信息,以便提供信息以指示样品是否与腺癌或鳞状细胞癌。

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