首页> 外国专利> VARIABLE COLOR TWO-PHOTON FLUORESCENT PROBE, METHOD FOR IMAGING THIOL ACTIVATION IN MITOCHONDRION USING SAME, AND METHOD FOR MANUFACTURING THE VARIABLE COLOR TWO-PHOTON FLUORESCENT PROBE

VARIABLE COLOR TWO-PHOTON FLUORESCENT PROBE, METHOD FOR IMAGING THIOL ACTIVATION IN MITOCHONDRION USING SAME, AND METHOD FOR MANUFACTURING THE VARIABLE COLOR TWO-PHOTON FLUORESCENT PROBE

机译:可变色两光子荧光探针,使用相同的成像方法检测线粒体硫醇活化的方法以及制造可变色两光子荧光探针的方法

摘要

The present invention relates to a two-photon fluorescent probe, and more particularly, to a two-photon fluorescent probe, a method for manufacturing same, and to a method for imaging thiols in mitochondria using same. The two-photon fluorescent probe, according to the present invention, injects two probes into one molecule, and thus can selectively dye the mitochondria and react with thiols, thereby generating intense fluorescence and imaging the distribution and activation of thiols inside mitochondria in a living cell or a healthy living tissue.
机译:双光子荧光探针技术领域本发明涉及双光子荧光探针,更具体地,涉及双光子荧光探针,其制造方法以及使用该探针对线粒体中的硫醇进行成像的方法。根据本发明的双光子荧光探针将两个探针注射到一个分子中,因此可以选择性地对线粒体进行染色并与硫醇反应,从而产生强烈的荧光并成像活细胞中线粒体内硫醇的分布和活化。或健康的活组织。

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