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METHOD FOR CULTURING ISLET CELLS AND METHOD FOR PREPARING CARRIER FOR ISLET CELL TRANSPLANTATION USING ATELOCOLLAGEN, AND ARTIFICIAL PANCREAS PREPARED USING SAME
METHOD FOR CULTURING ISLET CELLS AND METHOD FOR PREPARING CARRIER FOR ISLET CELL TRANSPLANTATION USING ATELOCOLLAGEN, AND ARTIFICIAL PANCREAS PREPARED USING SAME
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机译:胰岛细胞的培养方法和使用胶原蛋白的胰岛细胞移植载体的制备方法以及使用该方法制备的人造胰腺
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摘要
The present invention provides: a method for culturing islet cells and a method for preparing a carrier for islet cell transplantation by preparing cationic atelocollagen through the ionization of high purity atelocollagen and using the same; and an artificial pancreas prepared using the same. According to the present invention, it is possible to increase the survival rate of islet cells when culturing islet cells and/or glucose-dependent insulin secretion using cationic atelocollagen obtained through the ionization of high purity atelocollagen, or a cross-linked atelocollagen carrier, and glucose-dependent insulin secretion can be increased while simultaneously increasing the survival rate of the cultured and transplanted islet cells by providing a carrier for islet cell transplantation with excellent stability comprising cationic atelocollagen and alginates.
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