SOLID DISPERSION OF IMPROVED ADSORPTION PERFORMANCE AND PREPARATION THEREOF

摘要

A solid dispersion of improved adsorption performance and preparation thereof. Specifically, provided in the present invention is the solid dispersion. The solid dispersion comprises (A) serving as an active ingredient and represented by formula A, a compound or a derivative thereof, or a pharmaceutically acceptable salt, hydrate, or solvate thereof, and, (B) a hydrophilic macromolecule carrier, where the weight ratio between (A) and (B) is between 1:1 and 1:40. The solid dispersion provided in the present invention significantly increases in vitro dissolution of active ingredients, and greatly increases adsorption of the active ingredients for mammals, thus effectively reducing dosage.