A method of detecting 3 dimensional conformational change of a protein using surface plasmon resonance imaging system

摘要

The present invention is a two-dimensional changes in the tertiary structure of Bax protein that induces apoptosis in cancer cells to commit suicide relates to a sensor that can be measured directly on the chip , the sensor is a thin film of gold (gold thin film) antibody is an antibody binding to the chip surface , surface plasmon resonance (surface plasmon resonance: SPR) protein structure using an imaging system it 's characterized by rapid changes on the gold film surface and easy to measure .