A pharmaceutical composition for treating gallbladder carcinoma, a method for inhibiting growth or invasion of gallbladder carcinoma and a method for treating gallbladder carcinoma

摘要

The present invention relates to a pharmaceutical composition for treating gallbladder carcinoma, and a method for inhibiting the growth and metastasis of gallbladder carcinoma and treating gallbladder carcinoma, using the same. An antibody or siRNA, shRNA or an antisense oligonucleotide of the present invention which recognizes an L1CAM protein on the surface of the gallbladder carcinoma cells and specifically binds to the gallbladder carcinoma tissue, and a pharmaceutical composition containing the same can inhibit the growth, infiltration and metastasis of gallbladder carcinoma and can induce apoptosis, and thus will be used prevent and treat gall bladder carcinoma more safely and effectively.