NEW SIGMA (Σ)-RECEPTOR LIGANDS WITH ANTIAPOPTOTIC AND/OR PROAPOPTOTIC PROPERTIES IN RELATION TO BIOCHEMICAL MECHANISMS OF CELL, POSSESSING NEUROPROTECTIVE, ANTICANCER, ANTIMETASTATIC AND ANTI-INFLAMMATORY ACTION IN CHRONIC INFLAMMATORY PROCESS

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: present invention refers to selective sigma-receptor ligands possessing prototypical biphase, antiapoptotic and proapoptotic activity in relation to normal neuronal and cancer cells, to a pharmaceutical composition based thereon, and to using the same for preparing the respective pharmaceutical products.;EFFECT: preparing the pharmaceutical products with anticancer, antimetastatic, anti-inflammatory, neuroprotective, anticonvulsant, antidepressive and nootropic analeptic or sedative action.;4 cl