首页> 外国专利> Composition, useful as drug, e.g. chemotherapeutic agent comprises a matrix comprising hydrophobic polymer, an active substance released during exposure to ionizing rays, and an additive increased radiosensitivity of system

Composition, useful as drug, e.g. chemotherapeutic agent comprises a matrix comprising hydrophobic polymer, an active substance released during exposure to ionizing rays, and an additive increased radiosensitivity of system

机译:用作药物的组合物,例如化学治疗剂包括基质,该基质包含疏水性聚合物,在暴露于电离射线期间释放的活性物质以及增加的系统放射敏感性的添加剂

摘要

Composition comprises (a) matrix comprising at least one hydrophobic polymer, (b) an active substance, intended to be released during exposure to ionizing rays, and (c) optionally at least an additive, and an additive intended to increase the radiosensitivity of the system. Independent claims are included for: (1) preparing a composition comprising: preparing a solution by introducing the hydrophobic polymer in one or a mixture of solvent; adding the component (b), and optionally the component (c) in the solution; and eliminating active substances from the solvent; (2) exposing an aqueous solution comprising the composition to ionizing radiation and releasing the component (b) in the surrounding medium; and (3) a medical device for delivering the component (b) comprising the composition. ACTIVITY : Virucide; Cytostatic. MECHANISM OF ACTION : None given.
机译:组合物包含(a)包含至少一种疏水性聚合物的基质,(b)打算在暴露于电离射线期间释放的活性物质,和(c)任选地至少一种添加剂,以及旨在增加其放射敏感性的添加剂。系统。包括以下独立权利要求:(1)制备组合物,所述组合物包括:通过将疏水性聚合物引入一种或多种溶剂的混合物中来制备溶液;在溶液中加入组分(b),和任选地加入组分(c);从溶剂中除去活性物质; (2)将包含所述组合物的水溶液暴露于电离辐射中,并在周围介质中释放组分(b); (3)用于递送包含所述组合物的组分(b)的医疗装置。活动:杀病毒剂;止细胞的。作用机理:未给出。

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