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High throughput of glucose-6-phosphate dehydrogenase, detection of high-sensitivity
High throughput of glucose-6-phosphate dehydrogenase, detection of high-sensitivity
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机译:高通量的6-磷酸葡萄糖脱氢酶,高灵敏度检测
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摘要
Methods for determining the amount of glucose-6-phosphate dehydrogenase in a biological sample of ("G6PDH") is provided herein. In addition, a method for diagnosing a G6PDH-related disorders such as pre-eclampsia and acute hemolytic anemia, as well as how to detect G6PDH deficiency, are also provided herein. In some embodiments, the applicant's teachings provide a method for detecting G6PDH deficiency in a subject. For example, includes a can be determined by mass spectrometry amount of G6PDH in a biological sample obtained from a subject, and comparing to a suitable control, the amount of G6PDH in a biological sample, the method, wherein, When the amount of G6PDH in the sample is less than the appropriate controls, G6PDH deficiency is detected.
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