Virus vector for prime / boost vaccine consisting of vaccinia virus vector and Sendai virus vector

摘要

PROBLEM TO BE SOLVED: To activate both cellular immunity and humoral immunity and to be used for the production of a prime / boost vaccine effective against infections and malignant tumors caused by pathogenic microorganisms, which are generally difficult to treat with vaccine. I will provide a. A viral vector for a prime / boost vaccine comprising the following (a) and (b): (a) a vaccinia virus vector that retains a gene encoding an immunogenic polypeptide in an expressible manner, (b) A Sendai virus vector capable of expressing a gene encoding an immunogenic polypeptide.