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COMPOSITION FOR PREVENTING OR TREATING DEMENTIA CONTAINING PRUNUS MUME EXTRACT

机译:预防或治疗含李母猫提取物的痴呆症的组合物

摘要

The present invention relates to a composition for preventing or treating dementia containing an extract of Prunus mume (Fructus Mume), and the Prunus mume extract of the present invention has outstanding effects in improving spatial recognition ability and in normalizing hippocampal damage (normalizing ERK phosphorylation, increasing ChAT and normalizing NF-kappa B) induced by chronic vascular brain damage in a vascular dementia animal model, and hence can be used to advantage as a medicinal product for preventing or treating dementia diseases and as a functional health food for preventing or alleviating dementia diseases that accompany vascular brain damage such as vascular dementia.
机译:本发明涉及一种用于预防或治疗痴呆的组合物,其包含李子提取物(I.Prunus mume )(F子),并且本发明的李子提取物(I.Prunus Mume)在血管性痴呆动物模型中改善由慢性血管性脑损伤引起的空间识别能力并正常化海马损伤(使ERK磷酸化正常化,ChAT升高和使NF-κB正常化),因此可有利地用作预防或预防药物治疗痴呆症,并作为预防或减轻伴随血管性脑损伤的痴呆症疾病(例如血管性痴呆症)的功能性保健食品。

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