首页> 外国专利> COMPOSITION AND KIT FOR THE DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT, WHICH MEASURE AN EXPRESSION LEVEL OF LIPOCALIN-2, AND METHOD FOR PROVIDING INFORMATION FOR THE DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT

COMPOSITION AND KIT FOR THE DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT, WHICH MEASURE AN EXPRESSION LEVEL OF LIPOCALIN-2, AND METHOD FOR PROVIDING INFORMATION FOR THE DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT

机译:用于诊断轻度认知障碍的组合物和试剂盒,其测量LIPOCALIN-2的表达水平,以及提供用于诊断轻度认知障碍的信息的方法

摘要

The present invention relates to a composition for the diagnosis of mild cognitive impairment, which includes a formulation measuring an mRNA or protein expression level of lipocalin-2 gene, to a kit for the diagnosis of mild cognitive impairment, and to a method for providing information for the diagnosis of mild cognitive impairment using the same. According to the present invention, by using the agent for measuring an mRNA or protein expression level of the lipocalin-2 gene, a patient having mild cognitive impairment can be specifically identified by measuring an expression level of lipocalin-2, which is higher in a group of patients having mild cognitive impairment than in both a normal group and a group of patients having Alzheimer's disease.; In particular, it is possible to distinguish between a group of patients having mild cognitive impairment and a group of patients having Alzheimer's disease
机译:诊断轻度认知障碍的组合物技术领域本发明涉及用于诊断轻度认知障碍的组合物,其包括测量lipocalin-2基因的mRNA或蛋白质表达水平的制剂,用于诊断轻度认知障碍的试剂盒,以及提供信息的方法。用于轻度认知障碍的诊断使用相同的方法。根据本发明,通过使用用于测量lipocalin-2基因的mRNA或蛋白质表达水平的试剂,可以通过测量lipocalin-2基因的较高表达水平来特异性地鉴定具有轻度认知障碍的患者。与正常组和患有阿尔茨海默氏病的患者组相比,具有轻度认知障碍的患者组;特别地,可以区分具有轻度认知障碍的一组患者和具有阿尔茨海默氏病的一组患者

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