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Methods of using Bacillus anthracis protective antigen sequences for vaccination
Methods of using Bacillus anthracis protective antigen sequences for vaccination
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机译:炭疽杆菌 I>保护性抗原序列进行疫苗接种的方法
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摘要
The invention relates to improved methods of producing and recovering B. anthracis protective antigen (PA), especially modified PA which is protease resistant, and to methods of using of these PAs or nucleic acids encoding these PAs for eliciting an immunogenic response in humans, including responses which provide protection against, or reduce the severity of, B. anthracis bacterial infections and which are useful to prevent and/or treat illnesses caused by B. anthracis, such as inhalation anthrax, cutaneous anthrax and gastrointestinal anthrax.
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