VIROSOMIC PREPARATION, USE OF A VIROSOMIC PREPARATION, KIT, AND METHODS FOR VACCINATING A HUMAN AGAINST INFLUENZA INFECTIONS, AND FOR VACCINATING MAMMALIAN INDIVIDUALS AGAINST INFLUENZA INFECTIONS

摘要

The invention relates to virosome-based influenza vaccines for the manufacture of medicaments that are administered intradermally in humans. The invention provides (trivalent) compositions comprising low doses of hemagglutinin (HA) antigen in a virosomal preparation that fulfill the immune response standards with respect to seroconversion rates, GMT-fold increase and protection rates, for use in vaccination set-ups.