Monoclonal antibodies that specifically bind to protein organics; isolated nucleic acid coding; vectors; cell skeleton, production methods; drug synthesis containing this substance; and drugs used for the treatment of neurological diseases (Div.Sol.N degree 459-09)

摘要

p Proteins that bind to RGM A, particularly monoclonal antibodies, and in particular, humanized versions of antibodies with CDR grafts, which have the ability to bind RGM A and prevent binding of proteins RGM to the RGM A receptor and other proteins that bind to RGM A, thus neutralizing the function of RGM A. These antibodies can be useful in the treatment of various states, including, but not limited to, sclerosis. multiple, traumatic brain injury in mammary glands, injuries to the spinal cord, stroke,Neurodegenerative diseases and schizophrenia; amp; nbs; / P