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Extracellular FZD8 domains and fusion molecules from extracellular FZD8 domains for use in the treatment of obesity and obesity-related disorders
Extracellular FZD8 domains and fusion molecules from extracellular FZD8 domains for use in the treatment of obesity and obesity-related disorders
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机译:细胞外FZD8结构域和细胞外FZD8结构域的融合分子,用于治疗肥胖症和肥胖相关疾病
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摘要
Methods of treatment using Fzd8 extracellular domains (ECDs), Fzd8 ECD fusion molecules, and/or antibodies that bind Fzd8 are provided. Such methods include, but are not limited to, methods of treating obesity and obesity-related conditions. Fzd8 ECDs and Fzd8 ECD fusion molecules are also provided. Polypeptide and polynucleotide sequences, vectors, host cells, and compositions comprising or encoding such molecules are provided. Methods of making and using Fzd8 ECDs, Fzd8 ECD fusion molecules, and antibodies that bind Fzd8 are also provided.
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