ANTICANCER AND ANTIMICROBIAL LIPOPEPTIDE BIOSURFACTANT ISOLATED FROM MARINE NOCARDIOPSIS SP. B4 AND COMPOSITIONS THEREOF.

摘要

In the present invention, we have disclosed a stable lipopeptide biosurfactant isolated from Nocardiopsis sp. B4. Biosurfactant produced by Nocardiopsis sp. B4 was found thermostable. Stable lipopeptide biosurfactant from Nocardiopsis sp. B4 was showed a wide activity against the pathogenic strains. We have reported the putative mechanism of cancer cell growth inhibition by biosurfactant, isolated from marine Nocardiopsis sp. B4 in a human cervical cancer cell line, HeLA. We evaluated the cytotoxic potential of biosurfactant in HeLa cervical cancer cell lines.