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Process for the early detection of recurrence after therapy for prostate cancer

机译:前列腺癌治疗后早期发现复发的方法

摘要

A method for detecting whether a patient has a biochemical recurrence in early stage (ES - BCR) otiene stable disease, comprising a) providing two or more samples obtained from the patient at 18 months after therapy parael prostate cancer ; b) measuring the PSA level in the sample using an immunoassay format for the PSA sándwichheterogéneo with a detection limit at least as low as 2.0 pg / ml, using dichoinmunoensayo in a sandwich format reaction polymerase chain (PCR) for generating laseñal; c) using the PSA level samples to determine a PSA value; where ES - BCR is detected if the PSA value is at least or exceeds a PSA indicator and the enfermedadestable is detected if the PSA value does not exceed the PSA indicator, wherein the PSA indicator is a rate of increase in [PSA] of about 2.0 pg / mL / month.
机译:一种用于检测患者是否具有早期生化复发(ES-BCR)丁烯稳定疾病的方法,该方法包括:a)在治疗后18个月内提供两个或多个从患者那里获得的样品,其中包括平行前列腺癌; b)使用夹心形式的反应聚合酶链中的二choinmunoensayo进行酶联免疫吸附测定,以检测限至少低至2.0 pg / ml的免疫检测形式测量样品中PSA的水平; c)使用PSA水平样本来确定PSA值;其中,如果PSA值至少等于或超过PSA指示符,则检测到ES-BCR;如果PSA值不超过PSA指示符,则检测到性能稳定,其中PSA指示符是[PSA]的增长率约为2.0 pg / mL /月。

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