A system using a helical retainer in the direct plication annuloplasty treatment of mitral valve regurgitation

摘要

A system for using a helical retainer in the treatment of mitral valve regurgitationby reshaping the mitral valve annulus using one or more plications of annulartissue each fixed by a retaining clip is described. The system includes four devicesto achieve such percutaneous direct plication annuloplasty. The first is a preferablyprolapsable crossing catheter (200). Second, a deflecting guide catheter (300)is used to provide a means for guiding the plication device into proper positionat the subvalvular region of the mitral valve annulus. Third, the plication device(400) is then used to make plications in at or near the subvalvular region of themitral valve annulus. Fourth, a helical retainer clip (500) deployed by the plicationdevice in order to retain the plicated tissue in the plicated form. Alternatively,the fourth device is a retainer delivery catheter (600) that enables deliveryof a helical retainer over the outside of the plication device.