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A NOVEL METHODOLOGY FOR ASSESSING THE BOUNDED-INPUT BOUNDED-OUTPUT INSTABILITY IN QT INTERVAL DYNAMICS: APPLICATION TO CLINICAL ECG WITH VENTRICULAR TACHYCARDIA
A NOVEL METHODOLOGY FOR ASSESSING THE BOUNDED-INPUT BOUNDED-OUTPUT INSTABILITY IN QT INTERVAL DYNAMICS: APPLICATION TO CLINICAL ECG WITH VENTRICULAR TACHYCARDIA
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机译:评估QT间隔动力学中有界输入有界输出不稳定性的新方法:在心室室颤的临床心电图中的应用
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摘要
The present invention is directed to a method for determining onset of ventricular arrhythmias using bounded-input bounded-output stability of QT interval (QTI) dynamics. The method of the present invention includes two parts. A first part of the method determines the dependence of each QTI on several prior QTIs and RR intervals (RRI). This determination is represented as an autoregressive model with exogenous input (ARX). A second part of the method determines the BIBO stability of the ARX model in the z-domain. The metrics associated with the first and second parts of the method are then used to predict onset of arrhythmia.
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