THE TECHNOLOGY OF LAYER CRYSTALLIZATION FOR CONTROLLING TOTAL GINSENOSIDE CONTENT IN RED GINSENG EXTRACT AND THE MANUFACTUR OF QUATIFIED RED GINSENG EXTRACT USING IT

摘要

The present invention relates to a method for isolating and purifying high purity red ginseng concentrate by a first and a second layer crystallization and a manufacturing method for quantifying the contents of 11 kinds of ginsenosides. The present invention comprises: a first layer crystallization step for mixing the red ginseng concentrate and ethanol, then layer crystallizing primarily; and a second layer crystallization step for mixing a first acquisition and ethanol again, then layer crystallizing secondarily. The present invention provides a technique for isolating and purifying total ginsenosides from the red ginseng concentrate effectively which has an effect in cutting the unit cost of production and which upgrades the specifications of red ginseng concentrate products using high purity total ginsenosides, thereby leading the world in various high value red ginseng products market. Especially, development of the high purity total ginsenosides ensures production of the red ginseng concentrate products containing quantified total ginsenosides, thereby providing high quality products in the future market of raw material for the medicine. [Reference numerals] (AA) Red ginseng concentrate;(BB,EE) 95% Ethanol;(CC) First layer crystallization;(DD) Purity of total ginsenosides: 8.5 to 92 weight%;(FF) Mixing;(GG) First crystallized mixture;(HH) Second crystallized mixture;(II) Quantitative standard red ginseng concentrate;(JJ) Second layer crystallization;(KK) Purity of total ginsenosides: 72 to 98 weight%;(LL) High purity total ginsenosides