COMPOSITION COMPRISING LIGULARIA FISCHERI TUREZ. EXTRACTS FOR ANTI-OBESITY

摘要

The present invention relates to a composition for preventing, ameliorating, and treating obesity. The composition containing an extract of Ligularia fischeri Turez. as an active ingredient exhibits an excellent activity in inhibiting cell differentiation of 3T3-L1 fat precursor cells and a high inhibitory activity on the expression of PPAR-, CEBP-, and aP2 genes as upstream transcription factors in association with fat cell differentiation, and shows an excellent effect of inhibiting fat accumulation, thereby effectively preventing, ameliorating, and treating obesity. Further, the composition is a natural material, thus has a very high level of safety for the human body.