Uses of Genes as a marker for the diagnosis of lymph node metastasis of gastric cancer

摘要

PURPOSE: A kit for diagnosing gastric cancer metastasis to lymph nodes using a marker for diagnosing gastric cancer metastasis to lymph nodes is provided to accurately and quickly determine gastric cancer metastasis to lymph nodes without surgical operation. CONSTITUTION: A composition for diagnosing gastric cancer metastasis to lymph nodes contains an agent which measures expression levels of one or more genes selected among HLA-DRB5, DACH1, IRX3, NEU1, CD7, YBX2, HOXA11AS, ITPKA, MICB, ENO3, ARID3A, LTB, NINJ2, C20orf100, NES, CENPN, ARHGAP4, FAM69B, SLC27A3, EFCAB4A, KIFC1, RASAL3, ABCB1,FOXA3, TEAD4, CKS1B, SLC39A8, TNC, ELOVL5, LOC730102, SLC26A6, AURKA, ICAM3, LOC729086, FYN, FLJ35776, SHD, BRI3BP, SLC37A4, INPP5E, HIST1H4H, GTF3A, C13orf23, MLH1, CD96, GRTP1, ETS1, FOXM1, TMEM156, EXOSC8, ZC3H3, LOC646753, ESPN, FLOT1, DTNA, SPTBN5, KBTBD12, VARS2, CD6, CENPJ, PIGP, LOC440595, LOC653650, BSPRY, ALDH6A1, MRPL43, C11orf74, PDCD2, RAC1, PCM1, HEPACAM2, IFT20, TMEM173, SH2D4A, ERLIN2, NXF3, ABTB1, MCPH1, TNFRSF10B, PCBD1, SDC1, EXTL3, SLC38A10, ZNF395, C17orf58, PTGFRN, WRB, EBP, C14orf4, TNFRSF10A, CCDC25, MIPOL1, AIG1, KCNK1, UBXN8, NRIP1, TFG, APPBP2, IFT74, DSG2, ASMTL, TMEM66, C21orf33, WDR23, TKT, SAV1, TMEM106B, SLC25A6, FUT6, LOC402251, DKFZp761P0423, NEIL2, ICAM2, DCAKD, LOC148430, LOC651149, PPP2R2A, FLJ43681, CNOT7, HOXC4, C8orf40, VWA5A, INTS10, PDPK1, BNIP3L, XK, C9orf167, PROSC, DDIT4, KLK12, LOC339352, FDFT1, GSTO2, ZNF185, SOX7, CTNNB1, ARSD, TRIM29, CCDC58, DEFB1, FAM3D, GABRP, and CA9.